5 Health Battles: What Disease Does Cameron Mathison Have? (Latest 2025 Update)

The question of "What disease does Cameron Mathison have?" has a two-part answer, spanning from his early childhood to his adult career as a beloved television host and actor. As of December 2025, the star is a survivor of two significant health challenges, most recently a battle with kidney cancer that began in 2019, which he has since publicly overcome, transforming his experience into a powerful platform for health advocacy. The most recent and severe diagnosis the *General Hospital* star faced was Renal Cell Carcinoma (RCC), the most common type of kidney cancer, which was discovered after he sought help for persistent gastrointestinal issues. His journey through diagnosis, a successful surgery, and recovery is a testament to the importance of early detection and listening to your body, a message he continues to share with his fans across the Hallmark and soap opera communities.

Cameron Mathison: Actor, Host, and Health Advocate (Biography)

Cameron Arthur Mathison is a Canadian-American actor and television host known for his long-running roles in daytime television and his work on the Hallmark Channel.

• Full Name: Cameron Arthur Mathison
• Date of Birth: August 25, 1969
• Place of Birth: Sarnia, Ontario, Canada
• Notable Roles: Ryan Lavery on *All My Children* (1997–2011), host of *Home & Family* on the Hallmark Channel, and Drew Cain on *General Hospital*.
• Career Highlights: Daytime Emmy nominee, co-host of *Entertainment Tonight*, and host of the game show *Battle of the Decades*.
• Family: Married to Vanessa Mathison, with two children.

The 2019 Diagnosis: Renal Cell Carcinoma (Kidney Cancer)

In September 2019, Cameron Mathison revealed he had been diagnosed with renal cell carcinoma (RCC), a form of kidney cancer. The diagnosis came after a period of struggling with what he initially believed were simple "gut issues" or gastrointestinal problems, prompting him to undergo an MRI.

The Discovery and Type of Cancer

The tumor was found on his right kidney. Doctors later estimated that the tumor may have been growing undetected for as long as a decade. The actor was fortunate that the pathology report following his surgery revealed the cancer was the "least aggressive form" of RCC.

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The Treatment: Partial Nephrectomy

Days after his public announcement, Mathison underwent a successful surgical procedure known as a partial nephrectomy. This procedure involves removing the tumor and a small margin of healthy tissue around it, while sparing the rest of the kidney. His surgery was performed by Dr. Inderbir S. Gill at Keck Medicine of USC, a renowned expert in the field.

The swift action and successful surgery meant the actor did not require further treatments such as chemotherapy or radiation. His focus immediately shifted to recovery and maintaining a healthy lifestyle, a commitment he has publicly shared with his followers.

Cameron Mathison's Health Status: The Latest Update

As of the most recent public updates, Cameron Mathison is cancer-free and reports feeling "so great." His journey has extended past the four-year mark since his diagnosis, and he continues to emphasize the importance of regular check-ups and being proactive about one's health.

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The actor’s recovery has been a source of inspiration, as he quickly returned to his demanding career, including his role on *General Hospital* and his hosting duties. He has become a staunch advocate for cancer research and early detection, often sharing encouraging messages with fellow survivors.

His experience highlights a crucial lesson: seemingly minor or persistent symptoms, like the gastrointestinal issues he experienced, can sometimes be the only indicator of a serious underlying condition like a slow-growing tumor. This is why he encourages everyone to be their own best health advocate.

The Childhood Battle: Legg-Calvé-Perthes Disease

While his kidney cancer battle is his most recent high-profile health challenge, it was not his first. At the age of two and a half, Cameron Mathison was diagnosed with Legg-Calvé-Perthes Disease.

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What is Legg-Calvé-Perthes Disease?

This is a rare, degenerative childhood hip disorder where the blood supply to the femoral head (the ball of the hip joint) is temporarily interrupted. Due to the lack of blood flow, the bone begins to die and collapse, a condition known as avascular necrosis.

Impact and Advocacy

Mathison had the disease in both hips, which required him to wear leg braces and use crutches for an extended period during his childhood. He has spoken candidly about the experience, including being bullied, and how it shaped his resilience. He has since partnered with organizations like the Legg Calve Perthes Foundation to raise awareness and support for children dealing with this rare disease, often sharing photos of himself in his childhood braces on Rare Disease Day.

A Life of Resilience and Health Advocacy

Cameron Mathison’s public health journey has made him a powerful voice for several causes. Beyond his work for kidney cancer and Perthes disease, he has also supported the Alzheimer's Association and various other charities, including being on the Board of Governors of Love Our Children USA.

His story serves as a vital reminder that health challenges can affect anyone, regardless of their public profile. By openly discussing his diagnoses—from a childhood degenerative bone disease to adult renal cell carcinoma—Mathison provides hope and practical advice, encouraging others to prioritize their well-being and seek medical attention for unusual or persistent symptoms.