The Full Despicable Me 4 Cast Revealed: 11 Stars Who Brought Gru's New Adventure To Life

The highly anticipated animated sequel, *Despicable Me 4*, has delivered a fresh chapter in the life of Gru and his expanding family, featuring a stellar ensemble of returning voice actors and exciting new Hollywood talent. As of December 10, 2025, the film's full cast and their respective characters have been confirmed, showcasing a brilliant mix of comedic veterans and rising stars who stepped up to voice Gru's newest nemesis, Maxime Le Mal, and the quirky new addition, Poppy Prescott. This comprehensive guide breaks down every major star and character, providing an in-depth look at the voices behind the Anti-Villain League's latest mission. The fourth installment of the main *Despicable Me* franchise sees Gru, Lucy, and the girls facing their biggest threat yet, forcing the entire family to go on the run and adopt new identities. The introduction of Gru's new baby, Gru Jr., adds a chaotic, yet heartwarming, dynamic to the story, which is perfectly complemented by the incredible voice acting talent, including the iconic return of Steve Carell, Kristen Wiig, and the Minions' own Pierre Coffin.

The Core Despicable Me 4 Cast: Gru's Family and Returning Heroes

The heart of the *Despicable Me* franchise has always been the unconventional family unit, and *Despicable Me 4* sees all the beloved characters return, with some minor changes to the voice cast for the girls, ensuring the continuity of Gru's family life.

• Steve Carell as Gru: The former supervillain turned Anti-Villain League (AVL) agent. Gru is now a full-time father and husband, dealing with the arrival of his son, Gru Jr., and the new threat posed by Maxime Le Mal.
• Kristen Wiig as Lucy Wilde: Gru's wife and fellow AVL agent. Lucy is the supportive, action-oriented mother who helps Gru navigate their new life on the run.
• Miranda Cosgrove as Margo: Gru and Lucy's eldest, most responsible adopted daughter. Margo often acts as the voice of reason in the family's chaotic adventures.
• Dana Gaier as Edith: The rebellious, mischievous middle daughter. Edith is known for her adventurous spirit and love for all things espionage.
• Madison Skyy Polan as Agnes: The youngest adopted daughter, known for her sweet nature and obsession with unicorns. Polan takes over the role from Nev Scharrel, who voiced Agnes in *Despicable Me 3* and *Minions: The Rise of Gru*.
• Pierre Coffin as The Minions: The inseparable yellow henchmen. Coffin, the director of the first two films, returns to voice the entire horde of Minions, including their powerful new forms, the Mega Minions.
• Steve Coogan as Silas Ramsbottom: The former head of the Anti-Villain League who has since retired.

The New Stars and Characters Shaking Up Gru's World

The fourth film introduces a host of high-profile actors and their memorable new characters who drive the plot forward. These new additions—including the main villain and a key new member of Gru's neighborhood—provide fresh challenges and comedic opportunities.

Will Ferrell as Maxime Le Mal

Maxime Le Mal is the central antagonist of *Despicable Me 4*. He is a charismatic, yet incredibly dangerous, supervillain who escapes from prison with a single goal: to seek revenge on Gru. Le Mal's history with Gru is a major plot point, and his sophisticated, arrogant demeanor makes him a formidable foe for the Anti-Villain League agent. Ferrell, a comedy legend known for films like *Anchorman* and *Elf*, brings his signature over-the-top comedic style to the character, contrasting perfectly with Gru's more grounded, family-man personality.

Sofía Vergara as Valentina

Valentina is Maxime Le Mal’s glamorous and equally formidable girlfriend and sidekick. Voiced by the internationally renowned actress Sofía Vergara, Valentina is deeply involved in Le Mal's schemes to get revenge on Gru. Her character adds a layer of stylish villainy and flair to the antagonist duo, making her a memorable addition to the rogues' gallery of the *Despicable Me* universe.

Joey King as Poppy Prescott

Poppy Prescott is a key new character and a major source of conflict and comedy for Margo. Voiced by the talented Joey King, Poppy is an aspiring supervillain who idolizes Gru's former life and is a new acquaintance in the suburban neighborhood where Gru's family is hiding. Her presence forces Gru to confront his past while trying to maintain his new, secret identity. The dynamic between Poppy's villainous ambitions and Gru's reformed life as an AVL agent is a central theme.

Stephen Colbert as Perry Prescott

Joining the cast is late-night host and comedian Stephen Colbert, who voices Perry Prescott, a character related to Poppy. Perry is part of the new neighborhood Gru and his family move into as they enter the witness protection program. Colbert's distinctive voice and comedic timing add a layer of suburban absurdity to Gru's new life. The film also features Patsy Prescott, another member of the Prescott family, further integrating the new characters into the domestic side of Gru's life.

The Mega Minions: A New Level of Chaos

While not a voice actor addition, no discussion of the *Despicable Me 4* cast is complete without mentioning the Mega Minions. In a major twist, a small group of Minions is accidentally exposed to a super-serum that grants them superpowers, transforming them into the Mega Minions. This new evolution provides the franchise with its most powerful Minions yet, each possessing unique abilities like super-strength, flight, and laser vision. Their introduction dramatically raises the stakes, turning the typically bumbling yellow creatures into genuine, albeit still chaotic, superheroes who play a crucial role in the final confrontation with Maxime Le Mal and Valentina. The Mega Minions represent a significant entity in the film, expanding the Minions' lore and giving them a more direct, action-oriented role in the Anti-Villain League's operations. This development is a core reason why *Despicable Me 4* feels fresh and unique, moving beyond the standard Minion antics and into full-blown superhero action.

Topical Authority: The Creative Team Behind the Voices

The success of *Despicable Me 4* is not only due to its star-studded voice cast but also the experienced creative team at Illumination. The film was directed by Chris Renaud, who directed the first two *Despicable Me* films, ensuring a return to the series’ classic tone and humor. The screenplay was penned by Mike White, known for his work on *School of Rock* and *The White Lotus*, and Ken Daurio, a veteran writer for the franchise. This combination of directorial experience and fresh, sharp writing is what allowed the new cast members, particularly Will Ferrell and Joey King, to shine in their roles and breathe new life into the beloved franchise. The focus on Gru's transition from a supervillain to a family man and AVL agent, while managing the arrival of Gru Jr., provides a rich, emotional core to the action-packed super-spy narrative. The inclusion of new talent like Joey King and the comedic genius of Will Ferrell and Sofía Vergara ensured that *Despicable Me 4* was a box-office success and a critical favorite, maintaining the high standards of the Illumination brand. The film’s exploration of themes like family, identity, and redemption—all filtered through a lens of high-stakes supervillainy—solidifies its place as a standout installment in the animated comedy genre.