The 7-Step Blueprint: How Bryan Johnson Reversed Hair Loss And Greying With A $2 Million Routine

Bryan Johnson’s quest for eternal youth, known as Project Blueprint, extends far beyond his diet and organ health; it's a meticulous, data-driven approach that even targets the seemingly cosmetic issue of hair loss and greying. As of December 17, 2025, his regimen is not based on traditional, passive treatments but a highly customized, multi-faceted stack of compounds, devices, and supplements designed to optimize follicular health and reverse the visible signs of aging.

The tech millionaire claims his comprehensive strategy has reversed his hair loss and grey hair by an astonishing 70% in under a year, a result he attributes to the synergy of FDA-approved treatments, cutting-edge technology, and a systemic focus on total body health. This deep dive reveals the exact components of the Blueprint hair care protocol, from the specific topical formulation to the daily devices he uses.

Bryan Johnson: The Biohacker Behind Project Blueprint

Bryan Johnson is an American entrepreneur, venture capitalist, and biohacker, best known for his ambitious and highly publicized anti-aging protocol, Project Blueprint. Born on March 5, 1977, Johnson’s career is marked by significant technological and financial successes.

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• Braintree (2007): He founded Braintree, an online payment processing company, which included the mobile payment service Venmo. He sold Braintree to PayPal in 2013 for a staggering $800 million in cash.
• Kernel (2016): Following the sale of Braintree, Johnson founded Kernel, a neurotechnology company focused on creating non-invasive devices to monitor and record brain activity, with the goal of making brain data mainstream.
• Project Blueprint (2021): Project Blueprint was born out of Johnson's personal struggles with depression and a desire to regain control over his health after the intense stress of building Braintree. The project is an extreme, data-driven self-experiment aimed at reversing his biological age and achieving peak human health, a mission that costs him over $2 million annually.

The Core of the Blueprint Hair Loss Reversal Protocol

The key to Johnson's success in reversing hair loss lies in his combination therapy, which targets the issue from multiple angles: blocking the hormone dihydrotestosterone (DHT), stimulating blood flow and follicle growth, and utilizing light energy for cellular regeneration. This is a highly personalized and intense regimen that goes far beyond a simple shampoo switch.

1. The Custom Topical Hair Formulation (Rx Serum)

The centerpiece of Johnson's daily hair care is a highly potent, custom-compounded topical serum. He applies 1 milliliter of this solution to his scalp every morning. This formulation is a cocktail of highly effective, evidence-based ingredients, many of which are FDA-approved for hair loss treatment.

Key Ingredients in Johnson’s Topical Formula:

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• Minoxidil USP (5% or 7%): A vasodilator that stimulates blood flow to the scalp and extends the anagen (growth) phase of the hair cycle.
• Finasteride USP (0.25%): A 5-alpha reductase inhibitor that blocks the conversion of testosterone to DHT, the primary hormone responsible for male pattern baldness.
• Caffeine USP (1%): Known to stimulate hair growth and counteract the suppressive effects of testosterone on hair follicles.
• Azelaic Acid: A natural DHT blocker that also has anti-inflammatory properties, supporting a healthier scalp environment.
• Latanoprost: A prostaglandin analog that can extend the growth phase of the hair cycle, similar to its use in eyelash growth.

This "stacking" of ingredients, which includes the two FDA-approved treatments (Minoxidil and Finasteride), is what sets the Blueprint protocol apart, maximizing the potential for hair regrowth and thickness.

2. Daily Scalp Massage and Application Technique

The application method is equally important. Immediately after applying the topical serum, Johnson performs a two-minute scalp massage using a silicone massager. This is not just a relaxing step; it is a functional component of the protocol.

• Enhanced Absorption: The massage helps to work the potent topical solution into the scalp, ensuring maximum absorption of the active ingredients.
• Increased Blood Flow: Scalp massage physically increases blood circulation, delivering more oxygen and nutrients to the hair follicles, which is critical for growth and vitality.

The Technological Edge: Red Light Therapy and Peptide Serums

Beyond the topical medication, Johnson integrates advanced technology and targeted supplements to further optimize his results. This is where the Project Blueprint approach truly leverages biohacking principles for hair longevity.

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3. Low-Level Laser Therapy (LLLT) with a Red Light Cap

A non-negotiable part of his daily routine is the use of Red Light Therapy (RLT), also known as Low-Level Laser Therapy (LLLT). He uses a device like the 302 Laser Cap for six minutes or a Celluma Pro RLT panel for five minutes daily.

• Mechanism: LLLT works by emitting specific wavelengths of red and near-infrared light that are absorbed by the mitochondria in hair follicle cells. This energy absorption is believed to stimulate cellular metabolism, increase blood flow, and promote tissue regeneration.
• Benefits: This therapy is clinically backed to regrow hair and is FDA-cleared for treating androgenetic alopecia (pattern baldness).

4. Blueprint Hair Peptide Serum

As part of his Blueprint product line, Johnson utilizes a specialized Hair Peptide Serum. This serum is formulated with a complex of up to eight different peptides, which are chains of amino acids (the building blocks of protein).

• Peptide Action: Peptides are crucial for cell-to-cell communication and can signal the scalp to produce more collagen and elastin, creating a healthier microenvironment for hair growth.
• Scalp Health: The serum focuses on overall scalp health, supporting the look of healthier hair from the root up.

5. Targeting Grey Hair with Mayraki and GR7

Johnson’s protocol is unique in that it also specifically addresses the issue of hair greying. He uses topical formulations like Mayraki and GR7 one to two times per week to help restore the natural color of his hair. This shows a holistic approach to hair longevity, not just focusing on density but also on pigment.

The Systemic Support: Supplements and Diet

Hair health is often a reflection of systemic health. Johnson's success is also underpinned by his comprehensive Project Blueprint supplement stack, which provides the necessary internal building blocks for robust hair growth.

6. Collagen and Creatine

Two specific supplements that directly contribute to the structural integrity of hair are taken daily:

• Collagen Peptides (25g daily): Collagen is a primary component of the dermis, the layer of skin that contains the hair follicles. Supplementing with collagen can strengthen the hair structure and improve the skin environment.
• Creatine (2.5g daily): While often associated with muscle building, creatine is also an amino acid derivative that can support cellular energy and may play a role in hair health.

7. Essential Vitamins and Minerals

While his daily stack of 34 pills covers a vast array of nutrients, key vitamins and minerals known to support hair health are integral to his regimen:

• Biotin: Often called the “hair vitamin,” Biotin (Vitamin B7) helps strengthen the hair structure and reduce breakage.
• Vitamin D: Essential for the hair follicle cycling process, as a deficiency is often linked to various forms of hair loss.
• Zinc and Iron: These minerals are vital for hair tissue growth and repair, and deficiencies are common causes of shedding.

The total Blueprint hair care stack is a testament to Bryan Johnson’s commitment to optimizing every biological function. By combining pharmaceutical-grade topical treatments (Finasteride, Minoxidil), physical stimulation (Scalp Massage), advanced light technology (RLT), and systemic nutritional support (Collagen, Peptides), he has created one of the most comprehensive and data-backed protocols for hair longevity in the world of biohacking.