The Arquette Sisters: 7 Shocking New Projects And The Family Dynasty's Enduring Legacy In 2025

The Arquette sisters, Patricia and Rosanna, remain one of Hollywood’s most compelling and influential sibling duos, a testament to a true acting dynasty that spans generations. As of late 2025, their careers are experiencing a massive resurgence, not just in front of the camera but also in new, powerful roles behind it, proving their artistic versatility and enduring relevance in a rapidly changing industry.

This article dives deep into the most current and updated information on their professional lives, from Patricia Arquette’s highly anticipated true-crime series to Rosanna Arquette’s slate of upcoming independent films, all while honoring the powerful legacy of their family, including the vital work of The Alexis Project.

The Arquette Sisters: Complete Biographical Profile & Family Dynasty

The Arquette family is a legendary American acting dynasty, tracing its roots back to vaudeville. The five Arquette siblings—Rosanna, Richmond, Patricia, Alexis, and David—all became professional actors, establishing a unique and powerful footprint in film and television. The sisters, Rosanna and Patricia, are the most decorated and visible members of this generation.

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Rosanna Arquette: Profile

• Full Name: Rosanna Lisa Arquette
• Born: August 10, 1959, in New York City, New York
• Parents: Lewis Arquette (actor) and Brenda Olivia "Mardi" Nowak (actress, poet, therapist)
• Career Highlights: Nominated for an Academy Award for *Desperately Seeking Susan* (1985), and starred in iconic films like *Pulp Fiction* (1994) and *After Hours* (1985). She is also a noted activist and was a key voice in the Me Too movement.
• Awards: BAFTA Award nomination for *Desperately Seeking Susan*, Best Actress at Mystfest for *Black Rainbow* (1991).

Patricia Arquette: Profile

• Full Name: Patricia Arquette
• Born: April 8, 1968, in Chicago, Illinois
• Parents: Lewis Arquette (actor) and Brenda Olivia "Mardi" Nowak (actress, poet, therapist)
• Career Highlights: Won an Academy Award for Best Supporting Actress for her 12-year commitment to Richard Linklater's *Boyhood* (2014). She is also acclaimed for her roles in *True Romance*, *Lost Highway*, and the television series *Medium* and *Severance*.
• Awards: Academy Award, BAFTA Award, two Primetime Emmy Awards, and three Golden Globe Awards.

Patricia Arquette’s True Crime Obsession and Directorial Pivot (2025 Updates)

Patricia Arquette, known for her deeply transformative roles, is currently dominating the prestige television landscape. Her work on the Apple TV+ series *Severance* has solidified her status as a powerhouse actor, but her latest projects for 2025 show a distinct move toward true crime and a major pivot into directing.

1. The Murdaugh: Death in the Family Limited Series

One of the most talked-about upcoming projects is the Hulu limited series centered on the Murdaugh family saga. Patricia Arquette is set to star in this new true-crime drama, which details the complex and shocking events surrounding the powerful South Carolina family. This role is a major acting vehicle for Arquette, allowing her to delve into the dark psychology of a real-life national scandal. The series is expected to be a massive draw for streaming audiences in 2025, further cementing her reputation for tackling complex, real-world narratives.

2. Teasing Severance Season 3

While an official release date for *Severance* Season 3 remains elusive, Arquette has been actively involved in promotional discussions, teasing the show’s continued deep dive into the mysteries of Lumon Industries. Her character, Harmony Cobel, is one of the most intriguing and terrifying antagonists on television. The show's massive critical success and Arquette’s Emmy-nominated performance ensure that any update on the third season is global entertainment news.

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3. Directorial Debut with Gonzo Girl

Beyond acting, Arquette is making her mark behind the camera. Her feature film directorial debut, *Gonzo Girl*, premiered at the Toronto International Film Festival (TIFF). This project is a significant step in her career, showcasing her ability to helm a full-length narrative. This move from a celebrated actor to a director is a crucial development in the Arquette legacy, following in the footsteps of her brother David Arquette, who has also directed.

4. Directing the Environmental Drama Love Canal

In addition to *Gonzo Girl*, Patricia Arquette is also attached to direct the feature film *Love Canal*. This project is an adaptation of a documentary about the infamous environmental disaster in Niagara Falls, New York. Taking on such a politically and environmentally charged subject demonstrates Arquette’s commitment to using her platform for impactful storytelling, aligning with her long-standing activism for social and economic equality.

Rosanna Arquette’s Independent Film Renaissance and Activism

Rosanna Arquette, an icon of 80s and 90s cinema, is experiencing a vibrant period of creative output, focusing heavily on independent and genre films. Her outspoken stance on social justice, particularly her role as one of the first women to speak out against Harvey Weinstein, continues to define her public persona and influence her artistic choices.

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5. The Sci-Fi Thriller FUTRA DAYS (2025)

Rosanna Arquette is set to star in the mind-bending sci-fi thriller *FUTRA DAYS*, which has a 2025 release window. This role places her back in the genre landscape, a space she has explored throughout her career, from *Pulp Fiction* to more avant-garde projects. The film’s premise is expected to be a high-concept exploration of technology and reality, appealing to the independent film circuit.

6. The Upcoming Comedy-Drama Ex-Husbands (2025)

Arquette is listed with a role in the upcoming comedy-drama *Ex-Husbands*, slated for a 2025 release. This project, often a staple of her filmography, showcases her ability to balance intense dramatic roles with lighter, character-driven ensemble pieces. Her participation ensures the film receives significant attention from industry insiders.

7. Corporate Retreat and The Moment (2026)

Looking ahead to 2026, Rosanna Arquette is attached to the thriller *Corporate Retreat* and the film *The Moment*. The diverse slate of projects—ranging from sci-fi to thriller and comedy—highlights her relentless work ethic and her ability to collaborate with both established and emerging directors. She is actively involved in the industry, including attending high-profile events like the Netflix "Black Rabbit" New York Premiere in September 2025.

The Arquette Legacy: Alexis Arquette Family Foundation and The Alexis Project

The Arquette sisters, along with their brothers David and Richmond, continue to honor the memory and legacy of their late sister, Alexis Arquette, a trailblazing transgender actress and activist who passed away in 2016. The family’s commitment to social causes is channeled through the Alexis Arquette Family Foundation and The Alexis Project.

The Alexis Project, established in 2016, is a vital initiative that provides specialized medical and mental health services to the LGBTQ+ community, particularly focusing on transgender individuals. This work reflects Alexis Arquette's fierce advocacy for equality and visibility. The sisters’ public support for this foundation ensures that the Arquette name is synonymous not just with Hollywood success, but with genuine, impactful social activism.

The Arquette acting dynasty continues its powerful run in 2025. With Patricia Arquette taking on directorial duties and leading high-stakes true-crime dramas, and Rosanna Arquette maintaining a strong presence in the independent film world, the sisters are proving that their influence extends far beyond their iconic film roles. They are actively shaping the future of cinema and television while upholding a profound legacy of social responsibility.