The Definitive 2024-2025 Guide: What Day And Time Does Grey's Anatomy Air?

The long-running medical drama Grey's Anatomy continues to anchor ABC's primetime schedule, and for the 2024-2025 television season, fans can officially tune in for new episodes of Season 21 on Thursday nights. The show maintains its familiar spot in the late-night block, providing a consistent schedule for viewers who follow the complex lives and careers of the surgeons at Grey Sloan Memorial Hospital.

As of December 15, 2025, the latest episodes of Grey's Anatomy Season 21 air on Thursdays at 10:00 p.m. Eastern Time (ET) / Pacific Time (PT) on ABC. The season premiered on September 26, 2024, and is currently in its midseason break, with the highly anticipated midseason premiere scheduled for early 2025. This guide breaks down the exact days, times, and streaming options you need to catch every moment of the drama.

The Core Team: Creator and Long-Running Cast Profile

The success of Grey's Anatomy is built on the foundation laid by its creator and the enduring presence of its core cast. Understanding their roles provides context for the show's incredible longevity and cultural impact.

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• Shonda Rhimes (Creator, Executive Producer): A television powerhouse and founder of Shondaland, Rhimes is the visionary behind the show's original concept. She is known for creating other successful dramas like Scandal and How to Get Away with Murder. Her distinct style of rapid-fire dialogue, complex relationships, and high-stakes drama defines the series.
• Ellen Pompeo (Dr. Meredith Grey): Pompeo served as the show's titular lead for nearly two decades, portraying the character from intern to Chief of General Surgery. While her role has been reduced in recent seasons (especially Season 21) as she pursues other projects, she remains an Executive Producer and often provides voiceovers, with occasional appearances to anchor the narrative.
• Chandra Wilson (Dr. Miranda Bailey): Dr. Bailey, known for her "The Nazi" nickname early in the series, is one of only two actors who have appeared in every single season as a main cast member. Wilson's character has evolved from a tough resident to the Chief of Surgery, representing the heart and conscience of Grey Sloan.
• James Pickens Jr. (Dr. Richard Webber): Pickens Jr. is the other remaining original cast member, portraying the former Chief of Surgery and mentor to many of the show's main characters. His character, Dr. Webber, is a crucial link to the hospital's history and a constant presence in the lives of the younger surgeons.
• Current Series Regulars: The ensemble for Season 21 includes fan favorites like Kevin McKidd (Dr. Owen Hunt), Caterina Scorsone (Dr. Amelia Shepherd), Camilla Luddington (Dr. Jo Wilson), and Kim Raver (Dr. Teddy Altman), alongside the new generation of interns.

The Official 2024-2025 Grey's Anatomy Schedule Breakdown

For viewers who prefer to watch live or catch the episode the very next day, the schedule is straightforward. The show's consistency on Thursday nights has been a staple of ABC's programming for years, making it easy for fans to track.

When New Episodes Air Live on ABC

The primary broadcast day for Grey's Anatomy is:

• Day: Thursday
• Time: 10:00 p.m. ET/PT
• Network: ABC (American Broadcasting Company)

The current Season 21 schedule is a two-part affair, typical of network television. The first half of the season aired from its September 26, 2024, premiere until the winter break in late 2024. The second half, or midseason, will resume in the new year.

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Key 2025 Return Date: The midseason premiere for Grey's Anatomy Season 21 is scheduled to air on Thursday, March 6, 2025, at 10:00 p.m. ET/PT. New episodes will then continue to air weekly on Thursdays until the season finale.

The Post-Broadcast Streaming Day

If you miss the live broadcast, the new episode is typically available to stream on Hulu immediately the following day. This means the new episode of Grey's Anatomy is available for on-demand viewing on:

• Streaming Day: Friday
• Platform: Hulu

Streaming and Binge-Watching: Where to Watch Every Season

The streaming landscape for Grey's Anatomy has evolved significantly in 2024 and 2025, offering viewers multiple ways to catch up on the previous twenty seasons or binge-watch the entire series.

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Hulu & Disney+ (The New Streaming Home)

Hulu has become the definitive home for the most current and future seasons of Grey's Anatomy. This is particularly important because new episodes from Season 21 are available on Hulu the day after they air on ABC. Furthermore, a major shift in 2024 saw all past seasons of the medical drama added to both the Hulu and Disney+ platforms in the US, consolidating the show's streaming rights under the Disney umbrella (which owns ABC, Hulu, and Disney+).

• Current Season (Season 21): Available on Hulu (day after air).
• Past Seasons (Seasons 1-20): Available on both Hulu and Disney+.

Netflix Availability

For many years, Netflix was the exclusive home for the back catalog of Grey's Anatomy. While the show is now also on Hulu and Disney+, the series remains available on Netflix in the US, allowing long-time subscribers to continue their binge-watching journey. However, new seasons (like Season 21 and the upcoming Season 22) are primarily directed to Hulu for next-day streaming.

The Thursday Night Block and the Station 19 Effect

For years, Grey's Anatomy was part of a powerful Shondaland crossover block with its firefighter spin-off, Station 19. This often meant viewers would tune in for two hours of connected drama on Thursday nights, with the storylines frequently intersecting.

The biggest recent change to the Thursday night schedule is the cancellation of Station 19. The spin-off concluded with its seventh season, meaning the two-hour crossover block that fans were accustomed to is now over. While this cancellation does not affect Grey's Anatomy's renewal status (it was renewed for Season 22, premiering in October 2025), it means the 10:00 p.m. ET/PT slot is now a standalone commitment, no longer preceded by a related medical-firefighter drama.

This shift emphasizes Grey's Anatomy's longevity and its ability to continue as a standalone anchor for ABC's programming, focusing entirely on the intense surgical cases and personal lives of the doctors like Dr. Meredith Grey, Dr. Miranda Bailey, and Dr. Richard Webber at Grey Sloan Memorial. New generations of characters, including the new batch of surgical residents, are now driving the main storylines.