The Ozempic Flip-Flop: Kelly Osbourne’s Contradictory Stance On The Weight Loss Drug

The conversation surrounding Kelly Osbourne and the weight loss drug Ozempic has become one of the most confusing and contradictory celebrity narratives of 2024 and 2025. The television personality, known for her candidness on her health struggles, has offered a public stance that has shifted dramatically, moving from outright denial of using the medication to becoming an enthusiastic "fan" of its effects. This deep dive explores the latest updates, her history of weight management, and the crucial distinction she makes between her own journey and the drug that has captivated Hollywood.

As of late 2024, Kelly Osbourne continues to address the relentless speculation that her dramatic weight loss is solely due to the use of semaglutide, the active ingredient in Ozempic. While she has consistently credited her 2018 gastric sleeve surgery and commitment to fitness, her recent comments on the popular drug have only fueled the fire, creating a complex and ever-evolving public health discussion.

Kelly Osbourne: Biography, Career Highlights, and Health Timeline

Kelly Michelle Lee Osbourne is a British television personality, singer, actress, and fashion designer who first rose to global prominence as the middle child of heavy metal icon Ozzy Osbourne and his wife, Sharon Osbourne.

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• Full Name: Kelly Michelle Lee Osbourne
• Born: October 27, 1984 (Age 41 as of late 2025)
• Place of Birth: Westminster, London, England
• Parents: Ozzy Osbourne (father) and Sharon Osbourne (mother)
• Siblings: Aimee Osbourne and Jack Osbourne
• Partner: Sid Wilson (Slipknot DJ)
• Child: Sidney (born 2022)
• Career Highlights:
  • 2002–2005: Starred in the MTV reality series The Osbournes, which documented her family’s life.
  • Music Career: Released her debut album, Shut Up (2002), which included the hit cover of "Papa Don't Preach."
  • 2009: Competed on Dancing with the Stars, finishing third.
  • 2010–2017: Served as a host and fashion critic on E!'s Fashion Police.
  • 2019: Appeared as the Ladybug on The Masked Singer.
  • 2023–Present: Co-hosts The Osbournes Podcast with her family.
• Health & Weight Loss Milestones:
  • 2018: Underwent gastric sleeve surgery, a procedure that removes a portion of the stomach.
  • Post-Surgery: Lost over 85 pounds (38 kg) following the surgery.
  • 2022–2024: Continued weight loss journey following the birth of her son, Sidney.

The Contradictory Narrative: Ozempic Denial vs. Endorsement

The core confusion surrounding Kelly Osbourne’s weight loss stems from a series of public statements that appear to be in direct conflict with one another. This "Ozempic Flip-Flop" has kept her name in the headlines throughout 2024 and 2025, highlighting the intense media scrutiny celebrities face over their bodies.

The Consistent Denial: "I Did Not Take Ozempic"

For months, Kelly Osbourne has been adamant that her weight loss is not a result of using Ozempic, or its sister drug Wegovy, which both contain the active ingredient semaglutide.

• The Gastric Sleeve Defense: She has repeatedly credited her 2018 gastric sleeve procedure for the initial and ongoing success of her weight management. She has stressed that the surgery is a "tool" and not a magic fix, requiring a complete lifestyle overhaul.
• The Post-Pregnancy Effort: Following the birth of her son in late 2022, she attributed further weight loss to diet, exercise, and the demands of new motherhood.
• April 2024 Statement: In interviews, she directly addressed the rumors, stating, "I know everybody thinks I took Ozempic. I did not take Ozempic. I don't know where that came from." She then clarified that her mother, Sharon Osbourne, was the one who publicly used the drug.

The Surprising Endorsement: Becoming a "Fan"

While denying personal use, Kelly Osbourne has recently changed her tune on the drug itself, shifting from a critical stance to one of open support, which is the key piece of fresh information from late 2024.

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• The Podcast Revelation: On a late 2024 episode of The Osbournes Podcast, Kelly shared that her opinion on Ozempic had evolved.
• The New Perspective: She explained that her previous negative views changed after she "met somebody who lost weight from Ozempic and it changed their life."
• Calling it "Amazing": In a separate 2024 interview with E! News, she reportedly went further, admitting to taking Ozempic and stating, "I think it's [Ozempic] amazing." This statement, though highly contentious and often contradicted by her other denials, cemented the drug's connection to her in the media.

This dual narrative—denying personal use while praising the drug’s effectiveness for others—is a nuanced position that many celebrities are adopting. It allows her to defend her own hard-earned results (from the gastric sleeve) while acknowledging the drug’s role in the wider weight loss landscape.

The Topical Authority: Gastric Sleeve, Semaglutide, and the Ozempic Effect

To fully understand Kelly Osbourne's journey, it is essential to distinguish between the two primary methods of significant weight loss involved in the public discussion: bariatric surgery and GLP-1 agonists (like Ozempic and Wegovy).

Gastric Sleeve Surgery (Sleeve Gastrectomy)

Kelly Osbourne’s primary weight loss tool is the gastric sleeve, a bariatric surgery she underwent in 2018.

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• Mechanism: The procedure involves removing about 75-80% of the stomach, leaving a banana-shaped "sleeve." This physically restricts the amount of food a person can eat.
• Hormonal Impact: It also removes the portion of the stomach that produces the majority of the hunger-stimulating hormone ghrelin, which helps reduce appetite.
• Long-Term Commitment: The surgery is a permanent anatomical change that requires lifelong commitment to dietary and lifestyle changes, which Kelly has consistently emphasized.

Ozempic (Semaglutide) and GLP-1 Agonists

Ozempic is the brand name for semaglutide, a medication originally developed to manage Type 2 diabetes. Its powerful side effect of appetite suppression led to its approval for chronic weight management under the brand name Wegovy.

• Mechanism: Semaglutide mimics a natural hormone called GLP-1, which targets areas of the brain that regulate appetite and food intake. It slows gastric emptying, making a person feel full longer.
• Side Effects: The drug is not without its complications. Kelly’s mother, Sharon Osbourne, has been vocal about the negative side effects she experienced, including severe nausea, vomiting, and diarrhea, as well as the difficulty of maintaining the weight loss after stopping the injections. Common side effects also include constipation and abdominal pain.
• Controversy: The drug has sparked controversy due to its high cost, limited supply for diabetes patients, and the pressure it puts on individuals to achieve an "ideal" body type.

Kelly Osbourne’s Message to Body Shamers and the Future of Her Journey

In response to the constant scrutiny and "mean" comments from trolls who insist she must have used a drug like Ozempic, Kelly Osbourne has adopted a defiant and powerful stance.

She has focused on shutting out the "noise" and celebrating her journey, which she views as a testament to her perseverance through surgery, sobriety, and motherhood. Her current message is one of personal acceptance and tuning out the opinions of others, stating that everyone is entitled to their opinion but she chooses not to internalize the negativity.

The "Kelly Osbourne Ozempic" saga is less about a clear-cut admission and more about the public grappling with the new reality of weight loss drugs. Her story serves as a high-profile case study in the intersection of bariatric surgery, new pharmaceuticals, and the intense pressure of celebrity life, leaving the public to decide which chapter of her evolving narrative they choose to believe.