Halsey’s Health Battle: 7 Major Chronic Illnesses And Her 2025 Chemotherapy Update

The American singer-songwriter Halsey has been remarkably open about a complex and ongoing health battle, revealing a series of chronic and often debilitating diagnoses that have profoundly shaped her life and career. As of December 2025, the most crucial and recent updates revolve around her treatment for a rare T-cell lymphoproliferative disorder and Lupus SLE, conditions that have required her to undergo chemotherapy while preparing for her upcoming global tour. This deep dive explores the full scope of her diagnoses, from the initial "EDS Trifecta" to the more recent, life-altering conditions, providing the most current information on her inspiring journey.

Halsey: A Brief Biography and Profile

Halsey, born Ashley Nicolette Frangipane, is one of the most influential and genre-bending artists of her generation. Her openness about mental health, sexuality, and chronic illness has made her a powerful voice for millions of fans worldwide. Her biography is a testament to resilience and artistic evolution.

• Real Name: Ashley Nicolette Frangipane
• Date of Birth: September 29, 1994
• Age (as of 2025): 31
• Place of Birth: Edison, New Jersey, U.S.
• Occupations: Singer, Songwriter, Actress, Activist, Author
• Pronouns: She/They
• Career Highlights: Multi-platinum albums like Badlands, Hopeless Fountain Kingdom, and Manic; numerous Billboard Hot 100 hits including "Without Me" and "Closer" (with The Chainsmokers).
• Early Health Battle: She was diagnosed with endometriosis, a painful disorder where tissue similar to the lining of the uterus grows outside the uterus, which she has undergone surgery for.

The Initial Chronic Illness Diagnoses: The EDS Trifecta

Halsey’s health journey became public following a series of hospitalizations and persistent symptoms that left her exhausted and searching for answers. The singer first shared a detailed list of chronic conditions that are often interconnected, sometimes referred to as the "EDS Trifecta" due to their frequent co-occurrence.

Ehlers-Danlos Syndrome (EDS)

This is a group of inherited disorders that affect connective tissues—primarily skin, joints, and blood vessel walls. For Halsey, this diagnosis explains her chronic joint pain, instability, and hypermobility.

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Postural Orthostatic Tachycardia Syndrome (POTS)

POTS is a blood circulation disorder characterized by an abnormally large increase in heart rate when a person sits up or stands. Symptoms include lightheadedness, fainting (syncope), fatigue, and brain fog. This condition is a major contributor to her struggles with energy levels and physical exertion, particularly on tour.

Sjögren’s Syndrome

Sjögren's syndrome is a chronic autoimmune disease that primarily attacks the glands that produce tears and saliva, leading to severe dryness. However, it can also affect other parts of the body, including the joints, thyroid, kidneys, and nervous system, contributing to systemic inflammation and pain.

Mast Cell Activation Syndrome (MCAS)

MCAS is a condition where mast cells—immune cells found throughout the body—release too many chemicals, leading to a wide range of symptoms including anaphylaxis, hives, abdominal pain, and severe allergic reactions. This condition complicates her ability to manage environmental factors and stress.

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Halsey has often stated that receiving these diagnoses, while scary, was a moment of validation. It provided a name for the years of unexplained suffering and allowed her to begin a targeted treatment plan.

The Latest Health Battle: Lupus and T-Cell Lymphoproliferative Disorder

In a significant and concerning update, Halsey revealed in 2024 (and provided further updates in 2025) that her health battle had escalated with two new and severe diagnoses: Lupus SLE and a rare T-cell lymphoproliferative disorder. This revelation came as she prepared for her "Back to Badlands" global tour, demonstrating her commitment to her career despite immense personal challenges.

Systemic Lupus Erythematosus (Lupus SLE)

Lupus SLE is the most common and severe form of lupus, a chronic autoimmune disease where the body’s immune system attacks its own tissues and organs. This can affect the joints, skin, kidneys, brain, and other systems. The diagnosis of Lupus SLE is particularly serious and often requires aggressive treatment to prevent organ damage.

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Rare T-Cell Lymphoproliferative Disorder (T-LPD)

This is arguably the most concerning of her recent diagnoses. A T-cell lymphoproliferative disorder is a group of diseases characterized by the uncontrolled production of lymphocytes (a type of white blood cell). This can lead to a host of serious issues, including the formation of tumors in the lymphatic system. Halsey has described this as a condition linked to an overproduction of certain immune cells.

2025 Treatment and Outlook: Chemotherapy and Resilience

The severity of the Lupus SLE and the T-LPD diagnoses required a major shift in her medical regimen. In 2025, Halsey shared a candid update with fans, confirming she had been undergoing chemotherapy treatments.

The use of chemotherapy, typically associated with cancer treatment, is also a standard protocol for treating severe autoimmune and lymphoproliferative disorders. It works by suppressing the immune system and stopping the rapid, uncontrolled growth of cells, including the overproduced T-cells that characterize her rare disorder.

Despite the grueling nature of chemotherapy, Halsey has maintained a public stance of resilience and optimism. She has openly discussed the physical and emotional toll, including the challenging experience of losing parts of her personality during treatment. Her transparency aims to raise awareness for these often-invisible chronic illnesses and to connect with others facing similar battles.

The singer also recently experienced a "medical emergency" and a "very scary" seizure, which further underscores the volatility of managing multiple complex chronic conditions. However, she continues to focus on her music and her upcoming tour, viewing her art as a source of strength and a platform for advocacy. Her journey is a powerful reminder that chronic illness is a relentless, day-to-day battle, but one that can be fought with immense courage and grace.