George Clooney's Unstoppable 2025: 7 Surprising New Projects, Casamigos’ Latest Launch, And The $1 Billion Humanitarian Mission

George Clooney remains one of Hollywood’s most dynamic and influential figures, consistently making headlines not just for his acting roles, but for his directorial ambition, entrepreneurial success, and high-impact global activism. As of December 2025, the Oscar-winner is experiencing a period of intense activity, promoting a highly anticipated new film, expanding his billion-dollar tequila empire, and hosting his foundation's major annual event in London, proving that his career is far from slowing down. This deep dive explores the freshest updates, newest projects, and the core entities driving the legendary actor’s life and work today.

The year 2025 has brought a renewed focus on George Clooney’s versatility, seeing him transition seamlessly from a major film release to business expansion and serious humanitarian work. His current slate of projects and public statements confirms his status as a modern polymath: a successful artist, a savvy businessman, and a dedicated advocate for human rights. From the buzz surrounding his latest film collaboration with a celebrated director to the continued expansion of his Casamigos brand, Clooney’s influence is pervasive across cinema, commerce, and global justice.

George Clooney: A Comprehensive Biography and Profile

George Timothy Clooney was born on May 6, 1961, in Lexington, Kentucky, to Nina Bruce and Nick Clooney, a former news anchor and television host. His early life was steeped in the world of broadcasting and entertainment, which laid the groundwork for his future career. After various small roles, his breakout moment arrived in 1994 with the hit medical drama ER, where he played the charismatic Dr. Doug Ross for five seasons.

• Full Name: George Timothy Clooney
• Date of Birth: May 6, 1961
• Place of Birth: Lexington, Kentucky, U.S.
• Occupation: Actor, Director, Producer, Screenwriter, Businessman, and Humanitarian
• Spouse: Amal Clooney (m. 2014)
• Children: Twins Ella and Alexander Clooney
• Breakout Role: Dr. Doug Ross in ER (1994–1999)
• Major Film Franchises: Ocean's Eleven, Ocean's Twelve, Ocean's Thirteen
• Key Directorial Works: Confessions of a Dangerous Mind, Good Night, and Good Luck., The Ides of March, The Midnight Sky
• Major Awards: Two Academy Awards (one for Best Supporting Actor for Syriana and one for Best Picture for producing Argo), a British Academy Film Award (BAFTA), and four Golden Globe Awards.
• Business Venture: Co-founder of Casamigos Tequila (sold to Diageo for up to $1 billion)
• Philanthropy: Co-founder of the Clooney Foundation for Justice (CFJ) with his wife, Amal Clooney.

The 2025 Film Slate: Jay Kelly, Call My Agent, and Director's Reflections

The current year is shaping up to be a significant one for Clooney on the screen, highlighted by a major collaboration and a return to the international comedy scene.

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The Buzz Around ‘Jay Kelly’

One of the most talked-about projects of 2025 is the coming-of-age dramedy Jay Kelly, directed by the acclaimed filmmaker Noah Baumbach. Clooney stars alongside Adam Sandler in the film, which has generated considerable buzz among film critics and fans alike. The project is a key element of Clooney’s current promotional circuit, showcasing his continued commitment to working with auteur directors on character-driven stories. The film is expected to be a major awards contender, solidifying Clooney's prestige as a leading man.

A Surprise Role in 'Call My Agent The Movie'

Clooney has also confirmed his involvement in the upcoming Netflix film, Call My Agent The Movie, an extension of the popular French series. Filming for the project reportedly began in Paris in early October 2025. This role is a fun, high-profile cameo that demonstrates his willingness to embrace international projects and his sense of humor, often a hallmark of his best work, such as the Ocean’s Eleven trilogy.

Producing and Directing Aspirations

Beyond his on-screen roles, Clooney's production company, co-founded with Grant Heslov, remains highly active. Upcoming projects include the documentary Surviving Ohio State, which he is co-producing, and the stage adaptation of his Oscar-nominated film, Good Night, and Good Luck., which is heading to Broadway. In a recent interview, Clooney reflected on the challenges of wearing multiple hats, confessing that he generally “hates directing himself,” a sentiment he shared while promoting his work on Jay Kelly.

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Casamigos and the Billion-Dollar Business Empire

While his film career thrives, George Clooney’s legacy as a business mogul continues to grow through Casamigos Tequila, the brand he co-founded with Rande Gerber and Mike Meldman. The company, which was famously sold to the beverage giant Diageo for a value of up to $1 billion, remains a core focus of his entrepreneurial identity.

New Product Launches: Casamigas Jalapeño Tequila

In a major 2025 update, Casamigos launched a new product: Casamigas Jalapeño Tequila. The launch was a high-profile collaboration with iconic supermodel and entrepreneur Cindy Crawford, who is Rande Gerber’s wife. This strategic partnership leverages the star power of both families, ensuring massive media coverage and market penetration.

Expanding the Ready-to-Drink Market

Further capitalizing on the convenience trend, Casamigos also announced the launch of new canned margaritas in July 2025. This move into the Ready-To-Drink (RTD) cocktail sector is a direct response to current consumer demand for premium, convenient beverages. The brand's continuous innovation, even under Diageo’s ownership, highlights the enduring influence of the founders' vision for a high-quality, accessible spirit.

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The Global Impact of the Clooney Foundation for Justice (CFJ)

Perhaps the most significant and consistent aspect of George Clooney’s public life is his work with the Clooney Foundation for Justice (CFJ), which he co-founded with his wife, the international human rights barrister Amal Clooney.

The Albies 2025: Shining a Spotlight on Justice

The foundation’s annual flagship event, The Albies, named after South African anti-apartheid champion Justice Albie Sachs, took place in London in 2025. This star-studded event is a critical platform, designed to "shine a protective spotlight" on courageous human rights defenders, journalists, and justice advocates from around the world. The 2025 honorees were celebrated for their unwavering commitment to accountability and their work to support victims of human rights atrocities.

Waging Justice for Women and Other Initiatives

Beyond The Albies, CFJ continues its core mission. In 2025, the foundation announced its latest cohort for the Waging Justice for Women fellowship, an initiative dedicated to advancing justice for women and girls globally. This work, along with the foundation's long-standing efforts to stop human rights atrocities in regions like Darfur, Sudan, showcases the Clooneys' deep-seated commitment to global justice.

Personal Reflections and Public Commentary

In his personal life, Clooney has recently shared reflections on aging and temperament. While promoting Jay Kelly, he mentioned that he feels “less angry” as he gets older, a sign of contentment and maturity. However, he has not shied away from political commentary. In 2024, he made headlines for his frank opinion on the US presidential election, specifically stating that he felt it was a “mistake” for Kamala Harris to replace Joe Biden in the race, demonstrating that his public voice remains as strong and opinionated as ever.