The Nurse Jackie Cast: Where Are They Now? The Shocking Sequel Update & 7 Stars' Latest 2025 Projects

The sharp, dark world of All Saints’ Hospital and its pill-popping anti-hero, Jackie Peyton, captivated audiences for seven seasons, but what has the iconic Nurse Jackie cast been doing since the show’s polarizing finale? The series ended in 2015, yet the conversation around the critically acclaimed Showtime dramedy is hotter than ever, especially with major news breaking in late 2024 and early 2025 about a potential return. This deep dive into the lives and careers of the main cast reveals a shocking sequel update and a list of fresh, current projects that prove these Emmy-winning actors are busier than ever.

Beyond the highly anticipated sequel, the stars who brought Jackie, Zoey, Dr. Cooper, and the rest of the unforgettable emergency room staff to life have secured roles in some of the biggest new shows and films of the 2024–2025 season. From major streaming service dramas to celebrated stage productions, the former cast of Nurse Jackie continues to dominate the entertainment landscape, maintaining their status as some of the industry's most respected talents.

The Core All Saints' Hospital Cast: A Complete Biography Profile

The success of the series was built on the incredible chemistry and dramatic depth of its ensemble. Here is a quick-reference guide to the main cast members who defined the seven-season run of Nurse Jackie, complete with their essential biographical details.

• The Facts Of Life Cast Where Are Eastlands Girls Now 2024 Updates 2tx8p

• Edie Falco (Jackie Peyton):
  • Born: July 5, 1963
  • Birthplace: Brooklyn, New York, USA
  • Key Roles: Carmela Soprano in The Sopranos, Jackie Peyton in Nurse Jackie, Abigail Thomas in Tommy.
• Merritt Wever (Zoey Barkow):
  • Born: August 11, 1980
  • Birthplace: Manhattan, New York, USA
  • Key Roles: Zoey Barkow in Nurse Jackie, Karen Duvall in Unbelievable, Mary Agnes McNamara in Godless.
• Peter Facinelli (Dr. Fitch Cooper):
  • Born: November 26, 1973
  • Birthplace: Ozone Park, Queens, New York, USA
  • Key Roles: Dr. Carlisle Cullen in the Twilight Saga, Dr. Fitch Cooper in Nurse Jackie, Maxwell Lord in Supergirl.
• Paul Schulze (Eddie Walzer):
  • Born: June 12, 1962
  • Birthplace: United States
  • Key Roles: Eddie Walzer in Nurse Jackie, Father Phil Intintola in The Sopranos, William J. Rawlins in The Punisher.
• Anna Deavere Smith (Gloria Akalitus):
  • Born: September 18, 1950
  • Birthplace: Baltimore, Maryland, USA
  • Key Roles: Gloria Akalitus in Nurse Jackie, Nancy McNally in The West Wing, Professor of Performance Studies at NYU.
• Eve Best (Dr. Eleanor O'Hara):
  • Born: July 31, 1971
  • Birthplace: Ladbroke Grove, London, UK
  • Key Roles: Dr. Eleanor O'Hara in Nurse Jackie, Princess Rhaenys Targaryen in House of the Dragon.
• Dominic Fumusa (Kevin Peyton):
  • Born: September 13, 1969
  • Birthplace: Dane County, Wisconsin, USA
  • Key Roles: Kevin Peyton in Nurse Jackie, Special Agent Ray Conlin in Homeland.

The Shocking Nurse Jackie Sequel Update for 2025

The biggest news for fans of the original series is the confirmed development of a sequel. While the show originally aired on Showtime, the new follow-up series is currently in development with Prime Video. This move to a major streaming platform signals a significant new chapter for the franchise, which ended its initial run in 2015.

Edie Falco is slated to reprise her Emmy-winning role as Jackie Peyton, the morally compromised nurse at the heart of the story. The revival is expected to pick up a decade after the original series finale, which famously left Jackie’s fate ambiguous following an overdose. Falco herself has provided updates, confirming the project is still alive and moving forward, though a specific premiere date has not been set for the 2025 television schedule.

The original series, which aired for seven seasons, gained a massive new audience when it became available for streaming, proving the enduring popularity of the character and the show's dark humor. The sequel’s storyline is currently under wraps, but the return of Jackie Peyton is guaranteed to explore themes of addiction, recovery, and the broken healthcare system from a modern perspective, making it one of the most anticipated television events for fans of prestige dramedy.

• The Chilling True Story 5 Key Facts About Richard Evonitz The Serial Killer Who Kidnapped Kara Robinson Chamberlain Xpjje

Where the Main Cast of Nurse Jackie Is Now: 2024–2025 Projects

While Edie Falco prepares for her return as the title character, the rest of the talented ensemble has been busy with their own high-profile projects, cementing their status as television and film veterans. The breadth of their work showcases their versatility, moving seamlessly from dark comedy to prestige drama.

Edie Falco (Jackie Peyton)

Beyond the sequel, Edie Falco has maintained a busy schedule on both screen and stage. In 2024, she starred in the family comedy film I'll Be Right There. She also lent her voice to the 2024 radio play It Happened Here 2024 alongside John Turturro and Tony Shalhoub. For 2025, Falco is scheduled to take on a new role in the New York stage and film lineup, further demonstrating her commitment to theater, the medium where she got her start. Her career trajectory, moving from The Sopranos to Nurse Jackie and now a major streaming revival, is a masterclass in television longevity.

Merritt Wever (Zoey Barkow)

The Emmy-winning actress who played the quirky, earnest student nurse Zoey Barkow has seen her career surge in recent years. Merritt Wever is set to appear in the 2025 film Christy. On the small screen, she has secured a recurring role in the highly anticipated 2025 season of the prestige Apple TV+ drama Severance, a major win for fans of her layered, nuanced performances. Her post-Nurse Jackie roles in Unbelievable and Godless have already established her as a powerhouse of dramatic acting.

• The Surprise Vegas Wedding And Shared Grief 5 Shocking Details Of John Schneider And Dee Dee Sorvinos Whirlwind Romance Ohirf

Eve Best (Dr. Eleanor O'Hara)

Eve Best, who played Jackie’s best friend and confidante Dr. Eleanor O'Hara, has become a fixture in one of the biggest fantasy dramas on television. She continues to star as Princess Rhaenys Targaryen in the HBO hit series House of the Dragon. For 2025, she is also set to lead a new drama, Wild Cherry, playing the role of Juliet Lonsdale, a project that highlights her versatility beyond the fantasy genre.

Peter Facinelli (Dr. Fitch Cooper)

The actor known for playing the charming but often clueless Dr. Fitch Cooper has expanded his career behind the camera. Peter Facinelli recently made his directorial debut in the comedy genre. Looking ahead to 2025, Facinelli is involved in the film The Unbreakable Boy, a project that demonstrates his commitment to diverse and emotionally resonant storytelling. Fans will also remember his iconic role as Dr. Carlisle Cullen in the Twilight Saga.

Dominic Fumusa (Kevin Peyton)

Dominic Fumusa, who played Jackie's long-suffering husband Kevin Peyton, has been active in various television roles. In 2024, he appeared as a guest star, Jack Wilson, in an episode of the CBS drama Elsbeth. Looking to the near future, Fumusa is slated to appear in the 2025 project Dexter: Resurrection, a continuation of the popular crime drama franchise, showcasing his ability to take on complex, dramatic roles.

Anna Deavere Smith (Gloria Akalitus)

Anna Deavere Smith, the celebrated playwright, actress, and professor who played the formidable hospital administrator Gloria Akalitus, continues to focus on her groundbreaking theatrical and academic work. Her 2024–2025 schedule includes serving as an Artist in Residence at Wesleyan University. Her new play, Love All, a work that explores historical and social themes, premiered in 2023–2024, reinforcing her status as a major cultural commentator and performance artist.

Paul Schulze (Eddie Walzer)

Paul Schulze, who played the pharmacist and Jackie's lover Eddie Walzer, has a long history in prestige television, including a recurring role in The Sopranos. While specific 2025 acting projects are not widely publicized, his previous major role as the villain William J. Rawlins in the Marvel/Netflix series The Punisher demonstrated his ability to command the screen in a high-stakes dramatic setting.