The Ultimate List: Katherine Heigl’s Latest Movies, TV Shows, And Her Surprising 2025 Career Shift

As of December 2025, Katherine Heigl’s career is undergoing one of its most fascinating transformations yet, moving seamlessly between major Hollywood productions and a surprising new focus on entrepreneurship and production. While she remains best known for her unforgettable turn as Dr. Izzie Stevens on *Grey's Anatomy* and her reign as the undisputed queen of romantic comedy films, her most recent work on the Netflix hit *Firefly Lane* reaffirmed her status as a compelling dramatic lead, and her next big screen project is already generating buzz. This deep dive examines the complete, up-to-date filmography of the Emmy Award-winning actress, from her early modeling days and breakout roles to her latest projects, including a highly anticipated musical rom-com and her work behind the camera as an executive producer. We'll explore the roles that defined her career, the television series that brought her back to the small screen, and the exciting new ventures that mark her path for 2025 and beyond.

Katherine Heigl: Full Biography and Profile

Katherine Marie Heigl is an American actress, producer, and former fashion model whose career spans over three decades, marked by both major blockbuster success and critical acclaim in television.

• Full Name: Katherine Marie Heigl
• Date of Birth: November 24, 1978
• Place of Birth: Washington, D.C., U.S.
• Spouse: Josh Kelley (m. 2007)
• Children: Naleigh Moon Kelley, Adalaide Marie Hope Kelley, Joshua Bishop Kelley Jr.
• Early Career: Began her career as a child model with Wilhelmina Models at the age of nine.
• Breakthrough Role (Film): Knocked Up (2007) as Alison Scott.
• Breakthrough Role (TV): Grey's Anatomy (2005–2010) as Dr. Izzie Stevens.
• Key Awards: Primetime Emmy Award for Outstanding Supporting Actress in a Drama Series for Grey's Anatomy (2007).
• Activism: Co-founder of the animal welfare organization, the Jason Debus Heigl Foundation.

The Rom-Com Queen’s Reign: Defining Film Roles

Heigl’s film career is heavily defined by her leading roles in the romantic comedy genre, which cemented her status as a bankable box-office star in the late 2000s. These films were instrumental in shaping the public's perception of her as a charming and relatable lead.

The first major success was the 2007 Judd Apatow-directed comedy Knocked Up, where she starred opposite Seth Rogen. The film, which explored the unexpected pregnancy of a career woman, became a critical and commercial hit. While Heigl later expressed some regret over comments she made about the film's perceived sexism, the role of Alison Scott remains one of her most recognized.

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This success was quickly followed by 27 Dresses (2008), a quintessential romantic comedy where she played Jane Nichols, a woman constantly a bridesmaid but never a bride. The film's global success solidified her position as the genre's leading lady.

She continued her run with The Ugly Truth (2009), starring alongside Gerard Butler, and Life as We Know It (2010), opposite Josh Duhamel. These movies, though often receiving mixed reviews from critics, consistently performed well commercially, demonstrating her appeal to a broad audience. Her ability to blend sharp wit with vulnerability made her a perfect fit for the 'rom-com queen' title.

From Seattle Grace to Tully Hart: Heigl’s TV Triumphs

While her film career was booming, Heigl's television work has provided the deepest and most critically acclaimed roles of her career, particularly her long-running stint in Shonda Rhimes' medical drama and her recent Netflix success.

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The Dr. Izzie Stevens Legacy on Grey’s Anatomy

Heigl’s portrayal of surgical resident Dr. Izzie Stevens on Grey's Anatomy is arguably her most iconic role. From 2005 to 2010, she was a central figure in the ensemble cast, earning her a Primetime Emmy Award in 2007. The character’s journey, which included a dramatic cancer storyline and a controversial exit from the show, remains a constant topic of discussion among fans of the long-running series. Her departure and the surrounding media coverage marked a significant turning point in her career trajectory.

The Return to TV: State of Affairs and Doubt

Following her exit from the medical drama, Heigl made several attempts to anchor new television series. She starred as CIA analyst Charleston Tucker in the political thriller State of Affairs (2014–2015) and later as a defense lawyer in the legal drama Doubt (2017). Though neither series achieved the longevity of her earlier success, they showcased her versatility in taking on more serious, demanding roles.

Firefly Lane: A Netflix Resurgence

Heigl's most recent major television success was the Netflix series Firefly Lane, which ran for two seasons, concluding in 2023. Based on the novel by Kristin Hannah, the show followed the decades-long friendship between the ambitious, free-spirited Tully Hart (Heigl) and the shy, dependable Kate Mularkey (Sarah Chalke). Heigl not only starred as Tully Hart but also served as an executive producer, giving her a greater creative stake in the project. The series connected deeply with audiences, becoming a major streaming hit and marking a successful return to a leading role in a critically and commercially popular show.

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Latest Updates: What’s Next for Katherine Heigl in 2025 and Beyond

The latest updates on Katherine Heigl's career demonstrate a shift in focus, balancing her acting commitments with new ventures in production and entrepreneurship, providing a fresh perspective on her professional life as of late 2025.

Upcoming Film Project: That’s Amore!

Heigl’s next major acting role is the musical romantic comedy film That's Amore!, which is currently in pre-production. This project is a highly anticipated return to the big screen, particularly the romantic comedy genre that made her a star.

• Genre: Musical Romantic Comedy
• Co-Stars: She is set to star alongside Hollywood veteran John Travolta, who plays Nick Venere, and the legendary Christopher Walken.
• Director: Nick Vallelonga, an Academy Award winner known for co-writing Green Book.
• Heigl’s Role: She will play Patty Amore, a woman who bumps into Nick Venere and forms a deep connection.
• Status: The film is in pre-production, and a specific release date is currently To Be Announced (TBA), though it is expected to be a major title in 2025 or 2026.

Entrepreneurship and Lifestyle Brand Focus

Beyond acting, Heigl has boldly moved into the entrepreneurial space. She has founded a lifestyle brand that focuses on giving back, which has been a primary focus since the conclusion of the *Firefly Lane* Netflix series. This new role as a founder and entrepreneur highlights her desire to leverage her platform for causes she cares about, particularly those related to her foundation, Jenny's Light, which supports animal welfare.

In late 2024, Heigl was also featured in a major campaign for Poise, aiming to destigmatize bladder leaks, further showcasing her commitment to using her visibility for public awareness and commercial partnerships.

Artistic and Production Ventures

Heigl’s creative pursuits are also expanding behind the camera and into the art world. She continues to executive produce many of her own projects, a move that gives her greater creative control over the stories she tells. Furthermore, an upcoming exhibition of new works by Katherine Heigl, titled “Mountain Love Song,” is scheduled to open at the Sundance Film Festival in January 2025, revealing a surprising new dimension to her artistic talents.

From her iconic run as a beloved TV doctor to her status as a romantic comedy queen, Katherine Heigl’s career has been one of constant evolution. With her latest film, That's Amore!, on the horizon and a clear focus on producing and her own lifestyle brand, she is proving that her future success lies not just in the roles she plays, but in the projects she chooses to create and the causes she champions.