5 Arquette Siblings: Their Latest 2025 Projects And Enduring Hollywood Acting Dynasty

The Arquette family remains one of Hollywood’s most fascinating and enduring acting dynasties, with all five siblings continuing to shape the entertainment landscape through their diverse projects. As of December 13, 2025, the family is experiencing a new wave of high-profile activity, from major blockbuster casting announcements to directorial debuts and acclaimed television roles, proving their collective star power is as potent as ever.

This deep dive into the Arquette clan—Patricia, David, Rosanna, Richmond, and the late Alexis—provides the most up-to-date look at their latest professional endeavors, their unique family history, and the powerful advocacy work that continues to honor their legacy, cementing their status as a Hollywood institution across four generations.

The Arquette Family Tree: A Biography of the Acting Dynasty

The Arquette family's deep roots in Hollywood trace back to their paternal grandfather, Cliff Arquette, a comedian famous for the character "Charley Weaver." The family is a tapestry of diverse cultural and religious backgrounds, with their father, Lewis, converting to Islam and their mother, Brenda, being Jewish and the daughter of a Holocaust refugee from Poland. This complex, artistic heritage has fueled the siblings' unique careers and personal lives.

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• Lewis Arquette (Father): Born Lewis Michael Arquette (December 14, 1935 – February 10, 2001). An actor, writer, and producer known for his roles in *The Waltons* and *Scream 2*. He converted to Islam.
• Brenda Denaut (Mother): Born Brenda Olivia Nowak (1939 – 1997). An actress, poet, and Jewish theatre manager. She was the daughter of a Holocaust refugee.
• Rosanna Arquette: (Born August 10, 1959). The eldest sibling. An Oscar-nominated actress and director known for *Pulp Fiction*, *Desperately Seeking Susan*, and *After Hours*.
• Richmond Arquette: (Born August 21, 1963). An actor known for supporting roles in films like *Zodiac* and *Fight Club*. He is also a writer and producer.
• Patricia Arquette: (Born April 8, 1968). An Academy Award-winning actress known for *Boyhood*, *True Romance*, and the TV series *Medium* and *Severance*.
• Alexis Arquette: (Born Robert Arquette, July 28, 1969 – September 11, 2016). An actress and transgender advocate known for her roles in *The Wedding Singer* and *Pulp Fiction*. Her life and transition were documented in *Alexis Arquette: She's My Brother*.
• David Arquette: (Born September 8, 1971). An actor, producer, and former professional wrestler, best known for his role as Dewey Riley in the *Scream* franchise.

Patricia Arquette’s Career Peak: From Directorial Debut to True Crime and Sci-Fi Thrillers (2025)

Patricia Arquette is arguably the most critically acclaimed of the Arquette siblings, and her career trajectory in 2025 highlights her versatility across acting and directing. She is currently maintaining her presence in one of television's most acclaimed series while expanding into new, high-stakes projects.

Her transition to a behind-the-camera role marked a significant milestone with her feature film directorial debut, *Gonzo Girl*, which premiered at the Toronto International Film Festival (TIFF). The film, based on the novel by Cheryl Della Pietra, explores the world of a young aspiring writer and a volatile literary icon.

On the acting front, Arquette continues to star in the critically acclaimed Apple TV+ series *Severance*, which has garnered widespread praise for its unique blend of sci-fi, thriller, and corporate satire. Her role as the enigmatic Harmony Cobel is a masterclass in controlled intensity and remains a cornerstone of her current work.

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Looking ahead to 2025, Arquette is set to star in the Hulu true-crime drama series *Murdaugh: Death in the Family*, a highly anticipated project that delves into the complex legal and criminal saga of the Murdaugh family. Furthermore, she has joined the cast of a new horror thriller alongside Tom Felton and is slated to star in Kenneth Branagh’s miniseries, *The Last Disturbance of Madeline Hynde*, showcasing her commitment to complex, often darker, narrative roles.

David Arquette’s Big Comeback: Scream 7, Wrestling, and Reviving Classic Characters

David Arquette, known globally for his role as Deputy Dewey Riley in the *Scream* franchise, has been extremely active in 2024 and 2025, balancing his acting career with his passion for professional wrestling and producing. His involvement in the new installment of the iconic horror series has generated significant buzz.

The major news dominating David Arquette’s 2025 headlines is his reported return to the *Scream* franchise for *Scream 7*, with Kevin Williamson announced as the new writer and director. While the film's release is anticipated for 2026, the casting news in early 2025 confirmed his renewed involvement, thrilling fans of the original series. This return solidifies his enduring connection to the franchise that defined a generation of horror.

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Beyond the world of Ghostface, Arquette has demonstrated his diverse interests by taking on the legacy of a classic cultural figure. He is actively working on a documentary about the legendary clown, Bozo, and is planning to revive the animated series, aiming to introduce the character to a new generation. This project highlights his role not just as an actor, but as a cultural preservationist and producer.

In film, his recent work includes the 2024 release of *The Unholy Trinity*, adding another credit to his extensive filmography. Arquette’s career remains a unique blend of mainstream acting, indie film, professional wrestling, and producing, illustrating a dynamic and unpredictable professional path.

Rosanna, Richmond, and Alexis: The Enduring Legacy of the Other Arquette Siblings (2024-2025)

While Patricia and David often capture the most headlines, their siblings, Rosanna and Richmond, continue their impactful work in the industry, while the legacy of Alexis Arquette is actively maintained through important advocacy work.

Rosanna Arquette: Active in Film and Advocacy

Rosanna Arquette, the eldest of the siblings, remains a fixture on the film festival circuit and in new releases. In September 2025, she was seen attending the New York Premiere of Netflix’s new series, *Black Rabbit*, keeping her profile high in the industry. Furthermore, Rosanna is slated to appear in a feature film set for the Sundance 2026 lineup, confirming her continued commitment to independent and thought-provoking cinema.

Like her siblings, Rosanna is a vocal advocate. She frequently participates in events honoring her late sister, Alexis, and continues to use her platform to speak on social issues.

Richmond Arquette: Producer and Actor

Richmond Arquette, known for his subtle but consistent presence in film and television, is forging a path as a writer and producer. A notable project for him in 2025 is a miniseries project focusing on the complex and tragic history of Jonestown and the Peoples Temple, indicating his focus on historical and dramatic content.

Richmond, alongside his siblings, was also a key figure at the September 2024 event for The Alexis Project, demonstrating the family's united front in supporting the foundation dedicated to their sister's memory.

The Alexis Arquette Legacy: The Alexis Project

The family's most profound collective project is the ongoing dedication to the memory of Alexis Arquette, who was a pioneering figure and vocal advocate for the transgender community. Though she passed away in 2016, her spirit and message are kept alive through The Alexis Project.

The Alexis Project, a foundation dedicated to serving the LGBTQ+ community, held a major, impactful tribute and fundraising event in September 2024. This event, attended by all the surviving siblings, showcases the family’s commitment to carrying on Alexis’s legacy of candor, activism, and support for those navigating their own transition journeys. The family’s transparency about Alexis’s life and struggles, documented in the film *Alexis Arquette: She's My Brother*, continues to be a powerful message of acceptance and love.