Where Are They Now? The Nurse Jackie Cast's Biggest Projects In 2024 And 2025

The iconic cast of Nurse Jackie, one of Showtime's most critically acclaimed dramedies, has continued to dominate both television and film since the series finale in 2015. With the show gaining new life on streaming platforms and talk of a potential sequel series, fan curiosity about the beloved ensemble—from the morally complex Jackie Peyton to the quirky Zoey Barkow—is at an all-time high. This deep dive, updated for December 2025, reveals where the stars of All Saints' Hospital have landed and their most exciting new projects.

The series, which ran for seven seasons, was a masterclass in dark comedy, exploring themes of addiction, healthcare system failings, and the duality of a brilliant but flawed protagonist. The success was largely due to the incredible talent of the Nurse Jackie actors, many of whom have gone on to win major awards and star in some of the biggest shows of the decade, including blockbuster fantasy epics and critically acclaimed dramas.

Edie Falco: The Life and Career of Jackie Peyton

The heart of the show was, of course, Edie Falco, whose portrayal of the pill-popping, fiercely protective nurse Jackie Peyton earned her one of her many Emmy Awards. Falco is a television legend, being the only actress to have won an Emmy for Best Actress in both a Comedy Series (Nurse Jackie) and a Drama Series (The Sopranos). Her career trajectory is one of the most distinguished in modern television history.

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• Full Name: Edith Falco
• Born: July 5, 1963, in Brooklyn, New York, U.S.
• Major TV Roles: Carmela Soprano in The Sopranos (1999–2007), Jackie Peyton in Nurse Jackie (2009–2015), Leslie Abramson in Law & Order True Crime: The Menendez Murders (2017), and Hillary Clinton in Impeachment: American Crime Story (2021).
• Key Awards: Falco is a four-time Emmy Award winner, a two-time Golden Globe Award winner, and a five-time Screen Actors Guild Award winner. She is the first actress to win a record 20 Screen Actors Guild nominations.
• Recent & Upcoming Projects: She starred in the Peacock series Bupkis, a fictionalized version of Pete Davidson's life, and lent her voice to the 2024 audio documentary It Happened Here 2024.

The Latest Career Moves for the All Saints’ Hospital Staff

The supporting cast of Nurse Jackie has been incredibly busy, with many actors achieving new levels of fame in major streaming and blockbuster projects. Their post-Jackie careers highlight their versatility, moving from hospital dramedy to everything from dark sci-fi to high fantasy.

1. Merritt Wever (Zoey Barkow)

Merritt Wever, who played the adorably quirky and earnest nursing student Zoey Barkow, has arguably had one of the most successful post-Jackie careers. She won an Emmy for her role as Zoey and has continued to deliver critically acclaimed performances. Most recently, Wever was nominated for an Emmy for her role in the Hulu series Tiny Beautiful Things. Fans are eagerly anticipating her next major television role.

• Current/Upcoming Projects: Wever is set to appear in the highly anticipated second season of the Apple TV+ sci-fi psychological thriller Severance, which is slated for release in 2025. She is also part of the cast for the upcoming film Christy.

2. Eve Best (Dr. Eleanor O’Hara)

The British actress who played Jackie's sophisticated, sharp-tongued best friend, Dr. Eleanor O'Hara, has found massive success in the world of epic fantasy. Eve Best is now instantly recognizable to millions of new fans for her powerful role as Princess Rhaenys Targaryen, "The Queen Who Never Was," in the HBO fantasy series House of the Dragon.

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• Current/Upcoming Projects: Best was a central figure in House of the Dragon Season 2, which premiered in mid-2024, showcasing her character's crucial storyline and heroic acts.

3. Peter Facinelli (Dr. Fitch Cooper)

Peter Facinelli's portrayal of the charming, slightly buffoonish, and often self-absorbed Dr. Fitch "Coop" Cooper was a fan favorite. Facinelli, already famous for the Twilight saga, has been focusing on a mix of acting and directing in recent years.

• Current/Upcoming Projects: Facinelli's recent film work includes the action flick Running with the Devil, where he starred opposite Nicolas Cage. He is also part of the cast of the 2025 film The Unbreakable Boy. He continues to appear at fan conventions, often related to his enduring role in the Twilight franchise.

4. Dominic Fumusa (Kevin Peyton)

Dominic Fumusa played Kevin Peyton, Jackie’s long-suffering husband, who had his own complex journey after discovering her addiction. Fumusa has maintained a consistent and busy career in television, often appearing in procedural dramas and crime series.

• Current/Upcoming Projects: Fumusa appeared as Jack Wilson in the 2024 CBS series Elsbeth and had a guest role in the 2023 FX series Justified: City Primeval. Looking ahead, he is slated to appear in the upcoming series Dexter: Resurrection in 2025.

5. Paul Schulze (Eddie Walzer)

Paul Schulze played Eddie Walzer, the pharmacist and Jackie's lover who supplied her with pills, a character who became increasingly important as the series progressed. Schulze is a veteran character actor known for his roles in The Sopranos and 24. Interestingly, his recent work has taken a turn into the music industry.

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• Current/Upcoming Projects: Schulze has been actively releasing music, with new singles like "Make It Better" and "No Way Out" dropping in 2024, and "Life with You" and other tracks anticipated for 2025.

6. Betty Gilpin (Dr. Carrie Roman)

Betty Gilpin joined the cast in later seasons as the ambitious and initially shallow Dr. Carrie Roman, who evolved into a more sympathetic character. Gilpin has become one of the most in-demand actresses in Hollywood, earning critical acclaim for her role in the Netflix series GLOW.

• Current/Upcoming Projects: Gilpin starred in the Netflix Western series American Primeval in 2024. She is also scheduled to make her Broadway debut, taking over the lead role in the acclaimed comedy Oh, Mary! in early 2025. She is also attached to the upcoming Netflix production Death by Lightning.

7. Anna Deavere Smith (Gloria Akalitus)

Anna Deavere Smith played Gloria Akalitus, the hospital administrator and a constant foil to Jackie. Smith is not only an actress but a renowned playwright, professor, and performance artist. Her work often focuses on social issues and has a significant presence in the academic world.

• Current/Upcoming Projects: Smith continues her work as a creative and educator, serving as the Center for the Arts Artist in Residence for the 2024–2025 academic year at Wesleyan University. She is also presenting a public reading of her new play, "This Ghost of Slavery."

The Latest Status on the Nurse Jackie Sequel Series

For years, rumors of a Nurse Jackie sequel or revival have circulated, and in a fresh update, it appears the project is still alive—but has changed hands. The potential sequel, which would pick up the story of Jackie Peyton roughly a decade after the original finale, was initially in development at Showtime.

The Big News: The sequel series project has officially moved from Showtime to Amazon MGM Studios, with Edie Falco still attached to reprise her iconic role. While there have been limited official updates since early 2024, the move to a major studio indicates that the project is still a priority, even if it has moved to the back burner for the time being. The continuation of Jackie's story, exploring her life 10 years later, remains a highly anticipated prospect for fans of the original series.

The enduring success of the Nurse Jackie cast is a testament to the show's brilliant writing and the powerful performances that anchored the dark, compelling narrative. Whether they are battling dragons, solving crimes, or returning to the stage, the actors who once walked the halls of All Saints' Hospital continue to prove their status as television royalty.